{"id":36062,"date":"2025-06-18T19:17:02","date_gmt":"2025-06-18T16:17:02","guid":{"rendered":"https:\/\/www.egemtv.com\/?p=36062"},"modified":"2025-06-18T19:17:07","modified_gmt":"2025-06-18T16:17:07","slug":"gidalarda-mayalanma-ve-kuf-sorunu-papatya-ve-gelincik-bazli-biyolojik-antimikotik-ajan-ile-cozulecek","status":"publish","type":"post","link":"https:\/\/www.egemtv.com\/?p=36062","title":{"rendered":"G\u0131dalarda mayalanma ve k\u00fcf sorunu papatya ve gelincik bazl\u0131 biyolojik antimikotik ajan ile \u00e7\u00f6z\u00fclecek"},"content":{"rendered":"<p>\u0130nsan hayat\u0131nda en \u00f6nemli sorunlar\u0131n ba\u015f\u0131nda yer alan g\u0131da g\u00fcvenli\u011fi ve saklama ko\u015fullar \u00fczerine \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcren Karya Farma HBX Ar-Ge ekipleri, do\u011fal kaynakl\u0131 biyoteknoloji \u00e7al\u0131\u015fmalar\u0131 ile \u00f6nemli bir e\u015fi\u011fin daha a\u015f\u0131ld\u0131\u011f\u0131n\u0131 duyurdu. Papatya ve gelincik bitkileri kaynakl\u0131 antimikotik ajanlarla geli\u015ftirilen HBX-HGM71 form\u00fclasyonunun g\u0131dalarda, maya ve k\u00fcf mikroorganizmalar\u0131na kar\u015f\u0131 etkili sonu\u00e7lar olu\u015fturdu\u011fu belirtildi.<br \/>\n<br \/>Karya Farma HBX Ar-Ge ekibinden Kimyager Asl\u0131 Akta\u015f, form\u00fclasyonun bilimsel altyap\u0131s\u0131 ile ilgili yapt\u0131\u011f\u0131 a\u00e7\u0131klamada &#8220;Papatya (Matricaria chamomilla) ve gelincik (Papaver rhoeas), fitokimyasal a\u00e7\u0131dan g\u00fc\u00e7l\u00fc i\u00e7eriklere sahip iki \u00f6zel bitkidir. Papatyan\u0131n apigenin, bisabolol, chamazulen, flavonoidler ve fenolik bile\u015fikleri; Gelinci\u011fin ise alkaloidler, antosiyaninler ve polifenolleri g\u00fc\u00e7l\u00fc antifungal ve antimikrobiyal etki sunar. Saccharomyces cerevisiae (ATCC 16404): G\u0131da ve i\u00e7ecek sanayinde kalite bozulmas\u0131na yol a\u00e7abilen mayad\u0131r. Aspergillus niger (ATCC 6275): Mikotoksin \u00fcretebilen siyah k\u00fcf; insan ve hayvan sa\u011fl\u0131\u011f\u0131 i\u00e7in toksik etkiler ta\u015f\u0131r. HBX-HGM71 form\u00fclasyonunda bu iki kaynak stabilize edilerek h\u00fccre zar\u0131n\u0131 destabilize eden, iyonik dengeyi bozan ve metabolizmay\u0131 blokajlayan bir antimikotik sistem olu\u015fturduk. Ayd\u0131n Ticaret Borsas\u0131 Mikrobiyoloji Analiz Laboratuvar\u0131\u2019nda ger\u00e7ekle\u015ftirilen testlerde; HBX-HGM71 form\u00fclasyonu, 10,5 milyar kob\/ml maya ve k\u00fcf mikroorganizmas\u0131na 1 dakikal\u0131k temasla uyguland\u0131. 48 saatlik ink\u00fcbasyon s\u00fcrecinde hi\u00e7bir \u00fcreme tespit edilmedi&#8221; diyerek bu \u00e7al\u0131\u015fma ile ilerleyen s\u00fcre\u00e7te insano\u011flunun en \u00f6nemli ihtiyac\u0131 olan g\u0131dalarda raf \u00f6mr\u00fcn\u00fcn g\u0131dan\u0131n en do\u011fal haliyle uzayaca\u011f\u0131n\u0131 ve \u00f6nemli bir sorunun da \u00e7\u00f6z\u00fcme kavu\u015faca\u011f\u0131n\u0131 belirtti.<br \/>\n<br \/>Testlerin G\u0131da M\u00fchendisi Fatma Kolda\u015f Dumanc\u0131 ve G\u0131da Y\u00fcksek M\u00fchendisi Ay\u015fe Nur Ediz taraf\u0131ndan b\u00fcy\u00fck bir titizlikle y\u00fcr\u00fct\u00fcld\u00fc\u011f\u00fcn\u00fc de kaydeden Akta\u015f, bu \u00e7al\u0131\u015fma ile sadece g\u0131da sanayinde raf \u00f6mr\u00fcn\u00fcn uzamayaca\u011f\u0131n\u0131 ayn\u0131 zamanda ila\u00e7 ve dermokozmetikte form\u00fclasyon stabilitesi ve sterilizasyonun sa\u011flanaca\u011f\u0131n\u0131, hayvanc\u0131l\u0131k ve yem sanayisinde ise mikotoksin riskinin \u00f6nlenece\u011fini kaydetti.<br \/>\n<br \/>\u00c7al\u0131\u015fmalar\u0131n\u0131 AD\u00dc Teknokent\u2019te s\u00fcrd\u00fcren ve 18 ayr\u0131 patente sahip olan Karya Farma HBX Ar-Ge\u2019nin yeni \u00e7al\u0131\u015fmas\u0131n\u0131n ba\u015fta g\u0131da, ila\u00e7 ve yem sekt\u00f6r\u00fc olmak \u00fczere bir \u00e7ok sekt\u00f6rde kullan\u0131lmas\u0131 hedefleniyor.<br \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0130nsan hayat\u0131nda en \u00f6nemli sorunlar\u0131n ba\u015f\u0131nda yer alan g\u0131da g\u00fcvenli\u011fi ve saklama ko\u015fullar \u00fczerine \u00e7al\u0131\u015fmalar\u0131n\u0131 s\u00fcrd\u00fcren Karya Farma HBX Ar-Ge ekipleri, do\u011fal kaynakl\u0131 biyoteknoloji \u00e7al\u0131\u015fmalar\u0131 ile \u00f6nemli bir e\u015fi\u011fin daha a\u015f\u0131ld\u0131\u011f\u0131n\u0131 duyurdu. Papatya ve gelincik bitkileri kaynakl\u0131 antimikotik ajanlarla geli\u015ftirilen HBX-HGM71 form\u00fclasyonunun g\u0131dalarda, maya ve k\u00fcf mikroorganizmalar\u0131na kar\u015f\u0131 etkili sonu\u00e7lar olu\u015fturdu\u011fu belirtildi. Karya Farma HBX&#8230;<\/p>\n","protected":false},"author":1,"featured_media":36063,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","footnotes":""},"categories":[124],"tags":[],"class_list":["post-36062","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim"],"_links":{"self":[{"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/posts\/36062","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=36062"}],"version-history":[{"count":1,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/posts\/36062\/revisions"}],"predecessor-version":[{"id":36064,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/posts\/36062\/revisions\/36064"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/media\/36063"}],"wp:attachment":[{"href":"https:\/\/www.egemtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=36062"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=36062"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=36062"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}