AD\u00dc Teknokent\u2019te faaliyetlerini s\u00fcrd\u00fcren ve birbirinden ilgin\u00e7 \u00e7al\u0131\u015fmalar\u0131 ile g\u00fcndeme gelen Karya Farma HBX Ar-Ge \u015fimdi de endemik bitkilerden olu\u015fturdu\u011fu \u00f6zel bitkisel nutras\u00f6tik bile\u015fim ile ba\u015fta stres olmak \u00fczere de\u011fi\u015fik nedenlerden dolay\u0131 hasar g\u00f6ren beyin h\u00fccrelerinin tamiri i\u00e7in koku olu\u015fturdu. Yap\u0131lan bu \u00e7al\u0131\u015fma ile alzheimer, parkinson, demans, epilepsi, MS ve ALS gibi sinir sistemi hastal\u0131klar\u0131n\u0131n \u00f6nlenmesinde ve semptomlar\u0131n hafifletilmesinin hedeflendi\u011fi belirtildi.
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Yapt\u0131klar\u0131 \u00e7al\u0131\u015fman\u0131n T\u00fcrk Patent ve Marka Kurumu Taraf\u0131ndan HBX-HPA1442(2020\/16279), numaras\u0131 ile tescillendi\u011fini belirten Karya Farma HBX Ar-Ge Kurucusu Hakan Ba\u015fl\u0131k, “Bu \u00e7al\u0131\u015fmada \u00f6zel bitkisel nutras\u00f6tik bile\u015fim olu\u015fturduk. Bu bile\u015fim ile n\u00f6rodejeneratif hastal\u0131klar\u0131n tedavisinde \u00f6nemli bir d\u00f6n\u00fcm noktas\u0131 olmay\u0131 hedefliyoruz” dedi.
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Bug\u00fcne kadar yapt\u0131klar\u0131 \u00e7al\u0131\u015fmalara 18 ayr\u0131 patent ald\u0131klar\u0131n\u0131 ve insanl\u0131\u011fa faydal\u0131 olmak i\u00e7in \u00e7al\u0131\u015ft\u0131klar\u0131n\u0131 belirten Ba\u015fl\u0131k “N\u00f6rodejenerasyon; beynin sinir h\u00fccrelerinde ilerleyici hasar, i\u015flev kayb\u0131 ve nihayetinde h\u00fccre \u00f6l\u00fcm\u00fcne yol a\u00e7an karma\u015f\u0131k bir s\u00fcre\u00e7tir. HBX-HPA1442 bulu\u015fu; hastal\u0131\u011f\u0131n temelinde yer alan oksidatif stres, inflamasyon ve h\u00fccresel enerji yetersizli\u011fi gibi mekanizmalar\u0131 hedef alarak, h\u00fccresel d\u00fczeyde koruyucu ve onar\u0131c\u0131 etkiler olu\u015fturmay\u0131 ama\u00e7lamaktad\u0131r. Alzheimer ve parkinson hastal\u0131klar\u0131, \u00f6zellikle 65 ya\u015f \u00fcst\u00fc bireylerde s\u0131k\u00e7a kar\u015f\u0131la\u015f\u0131lan ve mevcut tedavilerde yaln\u0131zca semptomatik \u00e7\u00f6z\u00fcm sunulan \u00f6nemli sa\u011fl\u0131k sorunlar\u0131d\u0131r. HBX-HPA1442(2020\/16279) form\u00fclasyonu, bitkisel \u00f6z\u00fctlerin antioksidan ve n\u00f6roprotektif etkilerini bir araya getirerek hastal\u0131\u011f\u0131n ilerleyi\u015fini yava\u015flatmay\u0131 ve ya\u015fam kalitesini art\u0131rmay\u0131 hedeflemektedir. \u00c7al\u0131\u015fmada elde etti\u011fimiz \u00fcr\u00fcn\u00fc neb\u00fclizat\u00f6r cihazlar\u0131 arac\u0131l\u0131\u011f\u0131yla do\u011frudan solunum yoluyla verilmesi ile etken maddeler h\u0131zla sistemik dola\u015f\u0131ma kat\u0131l\u0131r. Akci\u011ferlerden direkt emilimle biyoyararlan\u0131m artar. Koku siniri (olfakt\u00f6r yol) \u00fczerinden merkezi sinir sistemi eri\u015fimi kolayla\u015f\u0131r. Bu \u00f6zellikleri sayesinde HBX-HPA1442, geleneksel oral formlar\u0131n kar\u015f\u0131la\u015ft\u0131\u011f\u0131 kan-beyin bariyeri engelini k\u0131smen a\u015fabilir ve hedef doku olan sinir sistemine \u00e7ok daha etkin ula\u015fabilir. HBX-HPA1442 ad\u0131n\u0131 verdi\u011fimiz bu \u00e7al\u0131\u015fma; MS, Alzheimer, Parkinson ve Beh\u00e7et hastal\u0131\u011f\u0131 gibi sinir sistemi ve ba\u011f\u0131\u015f\u0131kl\u0131k sistemi etkile\u015fimli hastal\u0131klarda kullan\u0131lmak \u00fczere tasarland\u0131” diyerek bu y\u00f6ntem ile haf\u0131za kayb\u0131 ve bili\u015fsel i\u015flev bozukluklar\u0131, motor koordinasyon problemleri, inflamasyon kaynakl\u0131 n\u00f6ronal hasarlar, serbest radikal hasar\u0131na ba\u011fl\u0131 h\u00fccre y\u0131k\u0131mlar\u0131 gibi sorunlar\u0131n ilerlemesini durdurmaya \u00e7al\u0131\u015ft\u0131klar\u0131n\u0131 belirtti.
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N\u00f6rodejeneratif hastal\u0131klarda genetik, epigenetik ve \u00e7evresel fakt\u00f6rlerin ortak rol oynad\u0131\u011f\u0131 g\u00fcn\u00fcm\u00fczde; ba\u011f\u0131\u015f\u0131kl\u0131k sistemini ve h\u00fccresel savunmay\u0131 destekleyen bu tarz bitkisel kombinasyonlar\u0131n \u00f6neminin giderek artt\u0131\u011f\u0131n\u0131 da kaydeden Ar-Ge ekibinden Kimyager Asl\u0131 Akta\u015f, “HBX-HPA1442 form\u00fclasyonu da tam bu noktada; bilimsel literat\u00fcrde yer alan antioksidan ve anti-inflamatuvar etki profiline sahip fitokimyasallar\u0131 bir araya getirerek yenilik\u00e7i bir tedavi deste\u011fi sunmaktad\u0131r. Klinik \u00e7al\u0131\u015fmalar preklinik faz protokolleri ve ileri faz insan denemeleri i\u00e7in HBX AR-GE ekibi haz\u0131rl\u0131klar\u0131n\u0131 s\u00fcrd\u00fcr\u00fcyor. HBX-HPA1442 form\u00fclasyonu sadece bir bitkisel bile\u015fim de\u011fil; ayn\u0131 zamanda v\u00fccudun kendi biyolojik ritmine ve nefes mekanizmas\u0131na uyum sa\u011flayacak \u015fekilde tasarland\u0131. Nefes \u00e7al\u0131\u015fmalar\u0131 s\u0131ras\u0131nda g\u00f6zlemledi\u011fimiz h\u00fccresel oksijenlenme art\u0131\u015f\u0131 ve vagus sinir aktivasyonuyla form\u00fclasyonun birle\u015fimi, sinir h\u00fccrelerinin enerji metabolizmas\u0131n\u0131 destekleyici g\u00fc\u00e7l\u00fc bir sinerji olu\u015fturuyor” dedi.
<\/p>\n","protected":false},"excerpt":{"rendered":"
AD\u00dc Teknokent\u2019te faaliyetlerini s\u00fcrd\u00fcren ve birbirinden ilgin\u00e7 \u00e7al\u0131\u015fmalar\u0131 ile g\u00fcndeme gelen Karya Farma HBX Ar-Ge \u015fimdi de endemik bitkilerden olu\u015fturdu\u011fu \u00f6zel bitkisel nutras\u00f6tik bile\u015fim ile ba\u015fta stres olmak \u00fczere de\u011fi\u015fik nedenlerden dolay\u0131 hasar g\u00f6ren beyin h\u00fccrelerinin tamiri i\u00e7in koku olu\u015fturdu. Yap\u0131lan bu \u00e7al\u0131\u015fma ile alzheimer, parkinson, demans, epilepsi, MS ve ALS gibi sinir sistemi hastal\u0131klar\u0131n\u0131n…<\/p>\n","protected":false},"author":1,"featured_media":35592,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_crdt_document":"","footnotes":""},"categories":[124],"tags":[],"class_list":["post-35591","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bilim"],"_links":{"self":[{"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/posts\/35591","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=35591"}],"version-history":[{"count":1,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/posts\/35591\/revisions"}],"predecessor-version":[{"id":35593,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/posts\/35591\/revisions\/35593"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=\/wp\/v2\/media\/35592"}],"wp:attachment":[{"href":"https:\/\/www.egemtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=35591"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=35591"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.egemtv.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=35591"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}